Figure 9.

Low expression of MCM2, MCM4, MCM6, and MKI67 is associated with increased probability of relapse-free survival [using the online survival analysis tool Kaplan-Meier Plotter (Gyorffy et al., 2010)].

The association between MCM2, MCM4, MCM6, and MKI67 expression and relapse-free survival of breast cancer patients was studied using the online survival analysis tool Kaplan-Meier Plotter. MCM2, MCM4, MCM6, and MKI67 mRNA expression was stratified into high or low expression using the median mRNA expression level as the cutoff point. Kaplan-Meier survival curve for MCM expression and the P value for log-rank test are shown alongside for each of the studied transcript expression (P < .0001).