Table 7.

Correlation between the Three Scoring Approaches Used during Scoring of the Protein Expression of Each of the Four Markers in Each Tumor Grade Using Kandall Rank Correlation

Grade I			Grade II			Grade III
	MCM2 IHS	MCM2%		MCM2 IHS	MCM2%		MCM2 IHS	MCM2%
MCM2%	0.553 (<.0001)		MCM2%	0.738 (<.0001)		MCM2%	0.795 (<.0001)
MCM2 Vis.Tis.S.	0.577 (<.0001)	0.483 (<.0001)	MCM2 Vis.Tis.S.	0.538 (<.0001)	0.600 (<.0001)	MCM2 Vis.Tis.S.	0.763 (<.0001)	0.734 (<.0001)
	MCM4 IHS	MCM4%		MCM4 IHS	MCM4%		MCM4 IHS	MCM4%
MCM4%	0.565 (<.0001)		MCM4%	0.742 (<.0001)		MCM4%	0.790 (<.0001)
MCM4 Vis.Tis.S.	0.374 (0.0002)	0.633 (<.0001)	MCM4 Vis.Tis.S.	0.619 (<.0001)	0.673 (<.0001)	MCM4 Vis.Tis.S.	0.721 (<.0001)	0.724 (<.0001)
	MCM6 IHS	MCM6%		MCM6 IHS	MCM6%		MCM6 IHS	MCM6%
MCM6%	0.693 (<.0001)		MCM6%	0.768 (<.0001)		MCM6%	0.736 (<.0001)
MCM6 Vis.Tis.S.	0.506 (<.0001)	0.686 (<.0001)	MCM6 Vis.Tis.S.	0.667 (<.0001)	0.778 (<.0001)	MCM6 Vis.Tis.S.	0.692 (<.0001)	0.687 (<.0001)
	Ki-67 IHS	Ki-67%		Ki-67 IHS	Ki-67%		Ki-67 IHS	Ki-67%
Ki-67%	0.498 (<.0001)		Ki-67%	0.503 (<.0001)		Ki-67%	0.669 (<.0001)
Ki-67 Vis.Tis.S.	0.448 (<.0001)	0.299 (.008)	Ki-67 Vis.Tis.S.	0.471 (<.0001)	0.557 (<.0001)	Ki-67 Vis.Tis.S.	0.560 (<.0001)	0.593 (<.0001)

%: percentage score.