Table 5.
Results of latent class model estimates (95% CI)
| Overall population (n = 680) | ||||
|---|---|---|---|---|
| All ages | Se | Spe | LR+ | LR− |
| Culture | 0.73 | 0.99 | 64.6 | 0.27 |
| Multiplex PCR assay | 0.99 | 0.98 | 45.7 | 0.01 |
| Nga-PCR assay | 0.89 | 0.96 | 22.02 | 0.11 |
| Age ≤ 17 years | Se | Spe | LR+ | LR− |
| Culture | 0.74 | 0.99 | 100 | 0.26 |
| Multiplex PCR assay | 0.94 | 0.98 | 45.5 | 0.01 |
| Nga-PCR assay | 0.88 | 0.97 | 34.5 | 0.12 |
| Age > 17 years | Se | Spe | LR+ | LR− |
| Culture | 0.69 | 0.98 | 28.6 | 0.31 |
| Multiplex PCR assay | 1.0 | 0.98 | 43.5 | ∞ |
| Nga-PCR assay | 0.93 | 0.91 | 10.5 | 0.07 |
PCR = polymerase chain reaction; LR+ = positive likelihood ratio; LR− = negative likelihood; Se = sensitivity; Spe = specificity. Estimates (CI= 95%) were calculated with MPlus software version 7.11. Without PCR prioritization means difference in volume (volume BC–volume PCR) ≥ −0.1mL. For computational reason, we selected only samples between 3 mL and 4 mL of blood for culture, eliminating, therefore, 36 samples.