Figure 6.

Effects of RILPL2 on BC cell proliferation and metastasis in vivo. (A-C) RILPL2-overexpressing MDA-MB-231 cells were injected into the flanks of nude mice. Tumor growth (A) and tumor volume (B) were measured on the indicated days. (C) Tumor weights were measured after mice were sacrificed. (D) RILPL2-overexpressing MDA-MB-231 cells were injected into the caudal vein of the nude mice. The mice were sacrificed 10 weeks later, and their metastatic lung nodules were quantified. Results are presented as means ± SD. The statistical significance was assessed by Student’s t-test; *P < 0.05, **P < 0.01.