Immunohistochemistry results of CK-19, COX-2, Galetin-3 and HBME-1 in each group. The protein expression of (A) CK-19, (B) COX-2, (C) Galectin-3, and (D) HBME-1 was detected in HT patients with multifocal PTC, with single PTC, and without PTC. Fields at 40× magnification were shown, and 1 representative from triplicates was shown for each staining.