Table 2.
Comparison of tissue immunohistochemical data between groups
| HT with multifocal PTC | HT with single PTC | HT alone | P | |
|---|---|---|---|---|
| N = 183 | N = 187 | N = 101 | ||
| n (%) | n (%) | n (%) | ||
| Immunohistochemistry | ||||
| CK19 | 0.011 (0.007, 0.013)b,c | 0.006 (0.002, 0.011)a,c | 0.003 (0.001, 0.004)a,b | < 0.001 |
| COX-2 | 0.005 (0.003, 0.009)c | 0.004 (0.002, 0.008)c | 0.002 (0.001, 0.004)a,b | < 0.001 |
| Galectin-3 | 0.009 (0.005, 0.021)c | 0.014 (0.009, 0.021)c | 0.003 (0.002, 0.004)a,b | < 0.001 |
| HBME-1 | 0.006 (0.004, 0.008)c | 0.006 (0.004, 0.007) | 0.006 (0.003, 0.006)a | 0.045 |
HT, Hashimoto’s thyroiditis; PTC, papillary thyroid carcinoma; CK19, cytokeratin 19; COX-2, cyclooxygenase 2; HBME-1, mouse anti mesothelioma. Continuous variables are presented as the median and IQR.
a
Significant difference vs. HT with multifocal PTC, P < 0.05.
b
Significant difference vs. HT with single PTC, P < 0.05.
c
Significant different vs. patients with HT alone, P < 0.05.