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. 2019 Aug 1;9(8):1722–1733.

Figure 5.

Figure 5

USP44 impedes pancreatic cancer cells growth through FBP1-MAPK pathway.( A and B) PANC-1 cells were transfected with indicated constructs for 48 h. The cells were collected for Western blot analysis (A) and MTS assay (B). Data are presented as the mean values ± SD (n = 3). **P < 0.01; ***P < 0.001. (C and D) PANC-1 cells were infected with indicated shRNAs for 72 h. The cells were collected for Western blot analysis (C) and MTS assay (D). Data are presented as the mean values ± SD (n = 3). **P < 0.01; ***P < 0.001. (E-G) PANC-1 cells were infected with indicated shRNAs for 72 h. The cells were harvested and injected subcutaneously into the nude mice. After 21 days, the tumors were collected, photographed and measured. Data are presented as the mean values ± SD (n = 4). n.s., not significant; *P < 0.05; ***P < 0.001.