Figure 5.

Effect of MPO inhibition on neuroprotective and apoptotic factors. (a) Western blots for Hsp70, pAkt and p53 levels in the ipsilateral striatum on day 3 after tMCAO in mice. β-actin was used for loading controls. Data shown are representative from each group. (b–d) Quantified result of Hsp70, p-Akt (Ser 473) and p53 levels, respectively. Data are mean ± SEM of percentage of protein levels with three to four animals in each group. ** p < 0.05, *** p < 0.001. ANOVA followed by Bonferroni’s post hoc test.