Table 1.

Mitochondrial respiratory activities and H₂O₂ production^a of brain mitochondria from P10 rats.

	Respiratory activity, nmol O2 × min−1 × mg−1	H2O2 release pmol × min− 1 × mg−1
Malate + Pyruvate (5 mM + 2 mM)	29.0 ± 4.3	124 ± 17**
+ADP (0.2 mM)	176.5 ± 14.4	44 ± 22
+Antimycin A (1µM)	7.6 ± 2.25	215 ± 14
Succinate (5 mM)	71.7 ± 2.1	535 ± 25**
+ADP (0.2 mM)	220.2 ± 21.7	59 ± 8
+FCCP (0.2 µM)	185.0 ± 17.2	113 ± 32
+Rotenone (1µM)	67.0 ± 6.0	112 ± 12
+Antimycin A (1µM)	8.5 ± 0.6	166 ± 16

^aMeasured simultaneously with respiration (see Methods). Three different preparations of mitochondria were used, each measured in four technical replicates.

^**p = 0.0005.