Table 2.

Regression Analysis Parameter Estimates Demonstrating the Relationships between Localized Parametric Response Mapping Classification and Micro–Computed Tomography Morphometry

	PRMfSAD			PRMEmph
Measurements	Estimate	SE	P Value	Estimate	SE	P Value
Terminal bronchiole morphometry
Terminal bronchioles per ml of lung	−0.007	0.003	0.02	−0.008	0.004	0.03
No. of obstructed bronchioles per ml of lung	0.004	0.002	0.008	0.00	0.002	0.99
Cross-sectional lumen area, mm2	−0.004	0.001	<0.001	−0.001	0.002	0.23
Wall area percentage	0.50	0.07	<0.001	0.33	0.10	0.002
Circularity	−0.001	0.0003	<0.001	−0.0007	0.0004	0.09
Alveolar attachment number per terminal bronchiole	−0.007	0.006	0.25	−0.02	0.009	0.01
Parenchymal morphometry
Mean linear intercept, μm	2.17	1.70	0.20	15.08	2.53	<0.001
Alveolar surface area, cm2/ml	−0.02	0.08	0.81	−0.17	0.06	0.003

Definition of abbreviations: Emph = emphysema; fSAD = functional small airways disease; PRM = parametric response mapping.

Bold indicates P < 0.05.