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. 2019 Aug 29;10:940. doi: 10.3389/fphar.2019.00940

Figure 4.

Figure 4

CCR7 is a direct target of miR-532-3p in TSCC. Putative wild-type (WT) and mutant (MUT) miR-532-3p binding sites in the 3’-UTR of CCR7. (A, B) Relative luciferase activities were analyzed in 293T cells co-transfected with WT (1 and 2) or MUT (1 and 2) reporter plasmids and miR-532-3p mimics or NC mimics. (C) CCR7 protein expression was ameliorated post-transfection miR-532-3p mimics in CAL-27 cell, whilst the expression of CCR7 was enhanced post-transfection miR-532-3p inhibitor. ** and ## means p < 0.01.