Figure 22.

Small and transient domains in complex biomembranes. (A) In a membrane with a total of 63 lipid types, GM1 (shown in red) clusters at the outer leaflet (ii), while phosphoinositides, shown in magenta, form small clusters in the inner leaflet (iii). Adapted with permission from ref (596). Copyright 2014 American Chemical Society. (B) Similar clustering of GM3 (shown in purple) in the outer leaflet (iii) and to a lesser degree that of phosphoinositides (yellow) in the inner leaflet (ii) in a 7-component membrane. Adapted with permission from ref (598). Copyright 2014 Koldsø et al. (https://creativecommons.org/licenses/by/4.0/legalcode).