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. 2019 Mar 12;119(9):5607–5774. doi: 10.1021/acs.chemrev.8b00538

Figure 73.

Figure 73

Example of peptide folding in the environment mimicking a translocon channel. Channel thickness was 1.2 nm. (A) In the absence of water in the channel, the peptide did not fold into a helix. (B) In the presence of water, on the other hand, the helix formed within 100 ns. Reproduced with permission from ref (1373). Copyright 2015, Springer Science Business Media New York.