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. 2019 Sep 4;21:102. doi: 10.1186/s13058-019-1183-3

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© The Author(s). 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Comparison between the cross-validated ROC curve for Clinical/DCE-MRI+DTI+interactions model and curves for Clinical/DCE-MRI-only and Clinical/DCE-MRI+DTI models. The interaction terms were size × ADC, type × ADC, size × FA, and type × FA and allowed the model to have different odds ratios for ADC and FA for each size × type subgroup. The bootstrap-adjusted AUC estimates were 0.76 (95% CI 0.71–0.83), 0.81 (95% CI 0.78–0.88), and 0.85 (95% CI 0.82–0.90), respectively. The Clinical/DCE-MRI+DTI+interactions model had a significantly higher AUC than the Clinical/DCE-MRI+DTI model (p = 0.018)