Table 1.
Annualized cost per patient
| Mild w/o inhibitors | Moderate w/o inhibitors | Severe w/o inhibitors | Inhibitors | Overall | |
|---|---|---|---|---|---|
| Children | |||||
| Direct costs | € 168 | € 295 | € 90,446 | € 349,973 | € 70,908 |
| Monitoring | € 168 | € 295 | € 724 | € 4,968 | € 835 |
| Prophylaxis | € 0 | € 0 | € 82,920 | € 40,478 | € 41,377 |
| ITI | € 0 | € 0 | € 0 | € 257,972 | € 21,670 |
| Minor bleedings | € 0 | € 0 | € 4,649 | € 38,469 | € 5,361 |
| Major bleedings | € 0 | € 0 | € 243 | € 8,086 | € 791 |
| Orthopaedic surgeries | € 0 | € 0 | € 1,910 | € 0 | € 875 |
| HIV co-infection | € 0 | € 0 | € 0 | € 0 | € 0 |
| Indirect costsa | € 0 | € 376 | € 2,347 | € 3,286 | € 1,379 |
| Unemployment | € 0 | € 0 | € 0 | € 0 | € 0 |
| Early retirement | € 0 | € 0 | € 0 | € 0 | € 0 |
| Work absence | € 0 | € 376 | € 2,347 | € 3,286 | € 1,379 |
| Total cost | € 168 | € 670 | € 92,793 | € 35, 260 | € 72,287 |
| Adults | |||||
| Direct costs | € 168 | € 5,661 | € 76,592 | € 279,429 | € 48,294 |
| Monitoring | € 168 | € 239 | € 644 | € 661 | € 402 |
| Prophylaxis | € 0 | € 5,422 | € 43,380 | € 48,576 | € 21,319 |
| ITI | € 0 | € 0 | € 0 | € 0 | € 0 |
| Minor bleedings | € 0 | € 0 | € 25,842 | € 224,212 | € 23,496 |
| Major bleedings | € 0 | € 0 | € 3,759 | € 4,923 | € 1,812 |
| Orthopaedic surgeries | € 0 | € 0 | € 1,910 | € 0 | € 775 |
| HIV co-infection | € 0 | € 0 | € 1,056 | € 1,056 | € 490 |
| HCV co-infection | € 0 | € 0 | € 0 | € 0 | € 0 |
| Indirect costs | € 310 | € 1,218 | € 6,884 | € 5,736 | € 3,443 |
| Unemployment | € 0 | € 51 | € 5,164 | € 5,164 | € 2,405 |
| Early retirement | € 0 | € 20 | € 30 | € 118 | € 22 |
| Work absence | € 310 | € 1,148 | € 1,690 | € 454 | € 1,016 |
| Total cost | € 478 | € 6,880 | € 83,476 | € 285,165 | € 51,737 |
| Overall | |||||
| Direct costs | € 168 | € 4,320 | € 80,055 | € 297,065 | € 53,948 |
| Monitoring | € 168 | € 253 | € 664 | € 1,738 | € 510 |
| Prophylaxis | € 0 | € 4,067 | € 53,265 | € 46,551 | € 26,333 |
| ITI | € 0 | € 0 | € 0 | € 64,493 | € 5,417 |
| Minor bleedings | € 0 | € 0 | € 20,544 | € 177,777 | € 18,962 |
| Major bleedings | € 0 | € 0 | € 2,880 | € 5,714 | € 1,557 |
| Orthopaedic surgeries | € 0 | € 0 | € 1,910 | € 0 | € 800 |
| HIV co-infection | € 0 | € 0 | € 792 | € 792 | € 368 |
| Indirect costs | € 233 | € 1,008 | € 5,750 | € 5,124 | € 2,927 |
| Unemployment | € 0 | € 38 | € 3,873 | € 3,873 | € 1,803 |
| Early retirement | € 0 | € 15 | € 23 | € 89 | € 17 |
| Work absence | € 233 | € 955 | € 1,854 | € 1,162 | € 1,107 |
| Total cost | € 401 | € ,5327 | € 85,805 | € 302,189 | € 56,875 |
aInformal caregivers