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. 2019 Feb 20;123(12):2609–2622. doi: 10.1021/acs.jpcb.8b10220

Table 1. Molecular Dynamics Simulations.

sim. ligand membrane length (μs)
1 orexin-A, TM5 POPC 3
2 orexin-A, TM5 POPC 1
3 orexin-A, TM5 POPC–CHOL 3
4 orexin-A, TM5 POPC–CHOL 1
5 orexin-A, TM7 POPC 3
6 orexin-A, TM7 POPC 1
7 orexin-A, TM7 POPC–CHOL 3
8 orexin-A, TM7 POPC–CHOL 1
9 suvorexant POPC 3
10 suvorexant POPC–CHOL 3
11 Nag26 POPC 3
12 Nag26 POPC 1
13 Nag26 POPC–CHOL 3
14 Nag26 POPC–CHOL 1
15 none POPC 3
16 none POPC–CHOL 3