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Nonsteroidal VDR ligands. The table summarizes the biological properties of the compounds: reference, 1,25(OH)2D3; (=) similar value; (+) >10× higher; (++) >100× higher; (+++) >1000× higher; (−) >10× lower; (--), >100× lower; (---), >1000× lower; VDR aff, VDR affinity; calcemia, [Ca2+] level changes in serum; 24OH trans, CYP24A1 transactivation activity; HL60 diff, HL-60 cell differentiation induction; MCF7 pr, MCF7 proliferation inhibition.
