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Side-chain-modified vitamin D analogs. The table summarizes the biological properties of the compounds: reference, 1,25(OH)2D3; (=) similar value; (+) >10× higher; (++) >100× higher; (+++) >1000× higher; (−) >10× lower; VDR aff, VDR affinity; Prolif inh, proliferation inhibition; Transac act, VDR transactivation activity; calcemia, [Ca2+] level changes in serum.
