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. 2019 Sep 4;20:32. doi: 10.1186/s12865-019-0305-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Effect of low-dose IL-2 combined with rapamycin on drug dose in patients with refractory SLE. a The change of prednison dosage at 0, 6th,12th and 24th week. Prednison; b the HCQ change at different week post treatment; c the MMF change at different week post treatment. One-way analysis of variance (ANOVA) test was performed, and the pairwise comparison was conducted using the LSD test. N_SLE = 50