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. 2019 Sep 5;38:390. doi: 10.1186/s13046-019-1379-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Restoration of PIP4K2B reverses the tumor-promoting effects of miR-3064 in PC cells. (a) PIP4K2B protein expression in AsPC-1 cells transfected with miR-3064 mimic with (or without) PIP4K2B expression vector, and in PaCa-2 cells transfected with miR-3064 inhibitor with (or without) PIP4K2B siRNAs. (b) Cell proliferation, invasion and sphere formation assays in AsPC-1 cells transfected with miR-3064 mimic with (or without) PIP4K2B expression vector. (c, d, e) Cell proliferation (c), invasion (d) and sphere formation assays (e) in PaCa-2 cells transfected with miR-3064 inhibitor with (or without) PIP4K2B siRNA-1 and siRNA-2. *P < 0.05