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. 2019 Sep 4;14:296. doi: 10.1186/s13018-019-1301-z

Table 1.

Clinicopathological variables and the expression of TfR1 and VEGF

TfR1 P VEGF P
Low(%) Mild(%) High(%) Low(%) Mild(%) High(%)
Sex Female 25 3(12.0) 10(40.0) 12(48.0) 0.332 5(20.0) 11(44.0) 9(36.0) 0.405
Male 28 8(28.6) 9(32.1) 11(39.3) 5(17.8) 8(28.6) 15(53.6)
Age ≥ 20 years 18 4(22.2) 4(22.2) 10(55.6) 0.306 3(16.7) 9(50.0) 6(33.3) 0.293
< 20 years 35 7(20.0) 15(42.9) 13(37.1) 7(20.0) 10(28.6) 18(51.4)
Tumor size < 5 cm 27 6(22.2) 10(37.0) 11(40.8) 0.919 6(22.2) 10(37.0) 11(40.7) 0.741
≥ 5 cm 26 5(19.2) 9(34.6) 12(46.2) 4(15.4) 9(34.6) 13(50.0)
Histologic grade* I 15 4(26.7) 8(53.3) 3(20.0) 0.04 4(26.7) 9(60.0) 2(13.3) 0.02
II 25 5(20.0) 10(40.0) 10(40.0) 5(20.0) 8(32.0) 12(48.0)
III 13 2(15.4) 1(7.7) 10(76.9) 1(7.7) 2(15.4) 10(76.9)
Distant metastasis* Yes 23 1(4.2) 11(47.8) 11(47.8) 0.029 1(4.4) 13(56.5) 9(39.1) 0.008
No 30 10(33.3) 8(26.7) 12(40.0) 9(30.0) 6(20.0) 15(50.0)
Enneking staging* I 12 8 (66.7) 3 (25.0) 7(36.9) < 0.001 6(50.0) 4(33.3) 2(16.7) 0.004
II 19 2 (10.5) 10(52.6) 21(43.8%) 2(10.5) 10(52.6) 7(36.9)
III 22 1 (4.5) 6 (27.3) 15 (68.2) 2(9.1) 5(22.7) 15(68.2)

Pearson’s chi-squared test was used. *P < 0.05