Fig. 8.

Expression of sex-biased transcription and epigenetic factors throughout development. Schematic heatmap representation of Tables 2 (a) and 3 (b) indicating expression and sex biases of transcription and epigenetic factors at each time point. Data was compiled from a female and b male ES cells, derived cardiac precursors (CP), hearts from 8.5, 9.5, and 10.5 days post coitum (dpc) embryos, neonates (p1), and adult mice (Ad). Each row is a specific transcription or epigenetic factor, with a total of 60 for females and 61 for males; the color denotes expression detected and enrichment in XX (red), XY (blue), or not biased (yellow). Group I: biased in ES cells, not expressed thereafter; groups II, III: biased in ES cells and same (II) or different (III) bias at other stages; group IV: biased after implantation but before gonadogenesis; group V: biased only after gonadogenesis