Table 3.
Male-biased expression of transcription and epigenetic factors
| Transcription factors and epigenetic and remodelling enzymes | ES | CP | 8.5 | 9.5 | 10.5 | p1 | Adult | Chr | Name |
|---|---|---|---|---|---|---|---|---|---|
| Egr4 | XY | 6 | Early growth response 4 | ||||||
| Cdx1 | XY | 18 | Caudal type homeobox 1 | ||||||
| E2f7 | XY | 10 | E2F transcription factor 7 | ||||||
| Eomes | XY | 9 | Eomesodermin | ||||||
| Evx1 | XY | 6 | Even-skipped homeobox 1 | ||||||
| Foxi3 | XY | 6 | Forkhead box I3 | ||||||
| Foxp4 | XY | 17 | Forkhead box P4 | ||||||
| Insm1 | XY | 2 | Insulinoma-associated 1 | ||||||
| Lin28a | XY | 4 | Lin-28 homolog A (C. elegans) | ||||||
| Mesp1 | XY | 7 | Mesoderm posterior 1 | ||||||
| Mixl1 | XY | 1 | Mix1 homeobox-like 1 (Xenopus laevis) | ||||||
| Nr6a1 | XY | 2 | Nuclear receptor subfamily 5, group A, member 1 | ||||||
| Pou2f3 | XY | 9 | POU domain, class 2, transcription factor 3 | ||||||
| Sox11 | XY | 12 | SRY (sex determining region Y)-box 11 | ||||||
| Sp5 | XY | 9 | Per-hexamer repeat gene 4 | ||||||
| Sp8 | XY | 12 | Trans-acting transcription factor 8 | ||||||
| T | XY | 17 | Brachyury, T-box transcription factor T | ||||||
| Tcf7 | XY | 11 | Transcription factor 7, T cell specific | ||||||
| Wiz | XY | 17 | Widely-interspaced zinc finger motifs | ||||||
| Ybx2 | XY | 11 | Y box protein 2 | ||||||
| Zglp1 | XY | 9 | Zinc finger, GATA-like protein 1 | ||||||
| Dnmt3b | XY | 2 | DNA methyltransferase 3B | ||||||
| Dnmt3l | XY | 10 | DNA (cytosine-5-)-methyltransferase 3-like | ||||||
| Phc1 | XY | 6 | Polyhomeotic 1 | ||||||
| Plac8 | XY | 5 | Placenta-specific 8 | ||||||
| Tdrd5 | XY | 1 | Tudor domain containing 5 | ||||||
| Bahcc1 | XY | 11 | BAH domain and coiled-coil containing 1 | ||||||
| Kdm6c | XY | XY | XY | XY | XY | XY | Y | Ubiq.transcribed tetratricopeptide repeat gene, Y chr | |
| Bcl6b | XY | XY | nb | 11 | B cell CLL/lymphoma 6, member B | ||||
| Irf8 | XY | XY | nb | 8 | Interferon regulatory factor 8 | ||||
| Arid1a | XY | XY | 4 | AT rich interactive domain 1A (SWI-like) | |||||
| Lef1 | XY | XY | XY | XY | 3 | Lymphoid enhancer binding factor 1 | |||
| Tbx20 | XY | XY | XY | XY | 9 | T-box 20 | |||
| Smarcd1 | XY | XY | 15 | SWI/SNF related, matrix assoc., actin-dep. reg. of chromatin d1 | |||||
| Zbtb7a | XY | XY | 10 | Zinc finger and BTB domain containing 7a | |||||
| Hif3a | XY | XY | XY | 7 | hypoxia inducible factor 3, alpha subunit | ||||
| Nfkb2 | XY | XY | XY | 19 | nuclear factor of κ light polypeptide enhancer B cells 2, p49/p100 | ||||
| Pbx2 | XY | XY | nb | 17 | Pre B cell leukemia homeobox 2 | ||||
| Prdm6 | XY | XY | 18 | PR domain containing 6 | |||||
| Id2 | XY | XY | 12 | Inhibitor of DNA binding 2 | |||||
| Dot1l | XY | XY | XX | 10 | DOT1-like, histone H3 methyltransferase (S. cerevisiae) | ||||
| Zfp296 | XY | XX | 7 | Zinc finger protein 296 | |||||
| Gata4 | XY | nb | 14 | GATA binding protein 4 | |||||
| Mycn | XY | nb | 12 | v-myc avian myelocytomatosis related og, neuroblastoma derived | |||||
| Hdac5 | XY | nb | 11 | Histone deacetylase 5 | |||||
| Nfxl1 | XY | nb | 5 | Nuclear transcription factor, X-box binding-like 1 | |||||
| Pax6 | nb | XY | 2 | Paired box 6 | |||||
| Brd4 | nb | XY | nb | 17 | Bromodomain containing 4 | ||||
| Carhsp1 | nb | XY | XY | XY | 16 | Calcium regulated heat stable protein 1 | |||
| Csde1 | nb | XY | XY | nb | nb | 3 | Cold shock domain containing E1, RNA binding | ||
| Mef2d | nb | XY | 3 | Myocyte enhancer factor 2D | |||||
| Atf5 | nb | XY | 7 | activating transcription factor 5 | |||||
| Bach2 | nb | XY | 4 | BTB and CNC homology, basic leucine zipper transcription factor 2 | |||||
| Cdc5l | nb | XY | 17 | Cell division cycle 5-like (S. pombe) | |||||
| Crebzf | nb | XY | 7 | CREB/ATF bZIP transcription factor | |||||
| Gm13139 | nb | XY | 4 | Zinc finger protein 991 | |||||
| Hmgb1 | nb | XY | 2 | Predicted gene, 21596 | |||||
| Hmgb2 | nb | XY | 8 | High mobility group box 2 | |||||
| Klf10 | nb | XY | 15 | Kruppel-like factor 10 | |||||
| Nfic | nb | XY | 10 | Nuclear factor I/C | |||||
| Nfkb1 | nb | XY | 3 | Nuclear factor of κ light polypeptide enhancer in B cells 1, p105 | |||||
| Pias2 | nb | XY | 18 | Protein inhibitor of activated STAT 2 |
ES embryonic stem cells; CP cardiac precursors; 8.5, 9.5, 10.5 days post coitum (dpc) embryonic hearts (single cell); p1 neonatal hearts; Chr chromosome; empty cells expression not detected; nb expressed but not biased