Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Evidence that light chain dissociates in MS source for AbbVie model ADC. (a) Full-range raw mass spectra show large signals for light chain+drug, but no significant signals for ADC minus light chain+drug. (b) Chromatogram with UV detection (top) and EIC based on light chain+drug (bottom). The blue arrows point to two peaks that changed intensities, and the inset depicts the structures for the isomers consistent with these intensity changes.
