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. 2019 Jul 22;30(16):2076–2086. doi: 10.1091/mbc.E19-02-0079

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© 2019 Jahed et al. “ASCB®,” “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society for Cell Biology.

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FIGURE 4: — Interactions of KASH domains with the outer nuclear membrane. (A) Total nonbonded interaction energies between all residues of the luminal KASH domains of KASH2, ANC-1, KASH5, and UNC-83, and the lipid membrane over simulation time. The conserved EEDY motif in KASH2 and ANC-1 interacts with the membrane. (B) Schematic representation of EEDY motif interacting with the outer nuclear membrane.