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. 2019 Sep 4;2(9):e199292. doi: 10.1001/jamanetworkopen.2019.9292

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Copyright 2019 Xu X et al. JAMA Network Open.

This is an open access article distributed under the terms of the CC-BY License.

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Figure 5. — This heatmap shows the significantly enriched pathways derived from the significantly differential germline variants between individuals with no cancer and patients with 13 cancer types (eMethods 8 in the Supplement). Columns represent APP, NK cell pathways, and NK cell–associated phenotypes, and rows represent cancer types. BLCA indicates bladder cancer; BRCA, breast cancer; COAD, colon cancer; HNSC, head and neck squamous cell carcinoma; KIRC, renal cancer; LGG, glioma cancer; LUAD, lung adenocarcinoma; LUSC, lung squamous cell cancer; PRAD, prostate cancer; SKCM, skin cancer; STAD, stomach cancer; THCA, thyroid cancer; and UCEC, endometrial cancer.