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Main concept. (A) Concept of integration a “friendly” network. (B) Scaffold with iPS cells and asymmetric microchannels integrates to similar surrounding network structure. 2D case can be done using current state microfluidics with PDMS chips. (C). Schematic view of microchannels (PDMS) that couples two neuronal cultures and provide unidirectional axon growth in between. (D) Scheme of iPS cells integration to developed network in a microfluidic chip.
