TABLE 2.

Differentially expressed genes in ΔcadA involved in PG and choline binding protein synthesis, and carbon utilization pathways.

	Locus		Fold
Gene	tag	Description	change
Peptidoglycan biosynthesis
glnH	SP_0609	Amino acid ABC transporter, amino acid-binding protein	–1.6
glnP	SP_0607	Amino acid ABC transporter, permease protein	–1.5
glnQ	SP_0610	Amino acid ABC transporter, ATP-binding protein	–1.7
Asd	SP_1013	Aspartate-semialdehyde dehydrogenase	–5.4
dapA	SP_1014	4-hydroxy-tetrahydrodipicolinate synthase	–4.8
lys9	SP_0919	Saccharopine dehydrogenase	–26.4
SP_1994	SP_1994	Aminotransferase, class I	–1.4
murI	SP_1881	Glutamate racemase	–1.7
Choline binding protein synthesis
pspA	SP_0117	Pneumococcal surface protein A	2.3
cbpA	SP_2190	Choline binding protein A	1.8
cbpI	SP_0069	Choline binding protein I	1.5
pcpA	SP_2136	Choline binding protein PcpA	2.3
Carbon utilization pathways
SP_0877	SP_0877	PTS system, fructose-specific IIABC components	2.6
SP_0645	SP_0645	Putative PTS system, IIA component	3.1
SP_0646	SP_0646	Putative PTS system, IIB component	2.6
SP_0647	SP_0647	Putative PTS system, IIC component	2.6
lacD	SP_1190	Tagatose 1,6-diphosphate aldolase	1.9
lacC	SP_1191	Tagatose-6-phosphate kinase	1.9
lacB	SP_1192	Galactose-6-phosphate isomerase subunit	1.7
lacA	SP_1193	Galactose-6-phosphate isomerase subunit	1.8
tktC	SP_2127	Transketolase, C-terminal subunit	97.9
tktN	SP_2128	Transketolase, N-terminal subunit	94.1
SP_2129	SP_2129	Putative PTS system, IIC component	81.5
SP_2130	SP_2130	Putative PTS system, IIB component	68.7