TABLE 3.

Associations between change in blood pressure and early events, functional outcome and death at 90 days, by baseline blood pressure

	Recurrent stroke/Neurological deterioration day 7a			mRS day 90b			Death at 90 daysa
	OR	95% CI	P	acOR	95% CI	P	OR	95% CI	P
SBP < 159 – n = 1568
>15% Decrease	1.22	0.67–2.20	0.249	0.82	0.59–1.13	0.220	0.81	0.42–1.56	0.043
5–15% Decrease	0.65	0.40–1.08		0.73	0.58–0.92	0.009	0.76	0.46–1.25
−5–5% Increase	1			1			1
>5% Increase	0.92	0.60–1.40		1.02	0.81–1.28	0.870	1.46	0.97–2.18
SBP 160–179 – n = 1447
>15% Decrease	0.61	0.34–1.10	0.008	0.80	0.60–1.07	0.128	0.89	0.48–1.67	0.039
5–15% Decrease	0.51	0.32–0.81		0.84	0.67–1.07	0.155	1.17	0.73–1.86
−5–5% Increase	1			1			1
>5% Increase	1.13	0.70–1.82		1.24	0.92–1.66	0.156	1.99	1.19–3.32
SBP 180–199 – n = 744
>15% Decrease	1.01	0.56–1.82	0.95	0.97	0.66–1.42	0.874	1.52	0.75–3.07	0.433
5–15% Decrease	0.90	0.53–1.51		0.87	0.63–1.19	0.380	0.83	0.43–1.59
−5–5% Increase	1			1			1
>5% Increase	1.11	0.72–1.71		0.82	0.52–1.2	0.416	1.04	0.45–2.42
SBP > 200 – n = 252
>15% Decrease	3.12	0.94–10.4	0.126	0.98	0.50–1.90	0.944	0.83	0.27–2.54	0.347
5–15% Decrease	1.02	0.31–3.38		0.71	0.38–1.33	0.287	0.37	0.12–1.23
−5–5% Increase	1						1
>5% Increase	2.27	0.60–8.66		0.83	0.35–1.97	0.667	0.81	0.21–3.10

acOR, adjusted common odds ratio; CI, confidence interval; mRS, modified Rankin scale; OR, odds ratio.

^aAnalysed using binary multivariate logistic regression.

^bAnalysed using ordinal logistic regression, adjusted for age, sex, premorbid mRS, history of previous stroke, history of diabetes, severity, stroke syndrome (total anterior circulation), stroke type (ischaemic, haemorrhagic, not stroke), SBP, alteplase, feeding status and time to randomization.