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. Author manuscript; available in PMC: 2019 Sep 5.
Published in final edited form as: Toxicol Sci. 2018 Nov 1;166(1):163–179. doi: 10.1093/toxsci/kfy190

Figure 5.

Figure 5.

Differential gene expression in the forebrain of the GD20 fetus. All PTU doses represent the maternal dose administered. A, The gene Camk4 was downregulated in response to 2 and 3 ppm PTU. B, Thyroid receptor beta (Thrb) was the only other differentially expressed gene in the GD20 fetus, and a significant change was only observed in the 3 ppm PTU dose group. An n 1/4 6–9 was analyzed per treatment; significant downregulation of both genes was determined by an overall ANOVA, a1/4 0.01. All asterisks represent significant dose effects as determined by mean contrast tests, a1/4 0.05. All error bars represent 6 SEM.