Figure 3.
Cell proliferation measured by PKH67 is presented. The results are presented as the median ratio and range of PKH67 values from three independent experiments in duplicate (n=6) between drug exposed cells and drug-free cells (control=1, dotted line). (A) Lidocaine significantly decreased cell proliferation in SW480 at 1,000 µM. (B) Ropivacaine did not significantly affect cell proliferation in SW480 at any concentration tested. (C) Lidocaine demonstrated no significant effect on cell proliferation in SW620 at any concentration tested. (D) Ropivacaine significantly decreased cell proliferation in SW620 at 1,000 µM. *P<0.05 vs. control.