Table 5.
Adaptive elastic net results: Adjusteda percent change (95% confidence interval) in 8-OHdG in association with an interquartile range difference in urinary phenol or phthalate metabolite concentration.
| Visit 1 |
Visit 2 |
Visit 3 |
Visit 4 |
|||||
|---|---|---|---|---|---|---|---|---|
| % Δ (95% CI) | p | % Δ (95% CI) | p | % Δ (95% CI) | p | % Δ (95% CI) | p | |
| 2,4-DCP | 7.84 (2.18, 13.8) | < 0.01 | 7.40 (−0.11, 15.5) | 0.05 | ||||
| 2,5-DCP | 11.3 (3.91, 19.3) | < 0.01 | 8.49 (−0.35, 18.1) | 0.06 | ||||
| BP3 | 7.38 (−0.59, 16.0) | 0.07 | 7.56 (−1.10, 17.0) | 0.09 | ||||
| Butyl PB | −6.91 (−14.7, 1.58) | 0.11 | ||||||
| Ethyl PB | −8.07 (−16.0, 0.64) | 0.07 | ||||||
| Methyl PB | 7.61 (0.47, 15.3) | 0.04 | ||||||
| Propyl PB | 6.37 (−2.19, 15.7) | 0.15 | 4.53 (−2.36, 11.9) | 0.20 | ||||
| Triclosan | ||||||||
| BPA | 3.78 (−2.87, 10.9) | 0.27 | 6.57 (−0.21, 13.8) | 0.06 | ||||
| ΣDEHP | 4.89 (−3.26, 13.7) | 0.25 | ||||||
| MBzP | 7.74 (0.70, 15.3) | 0.03 | 8.98 (2.20, 16.2) | < 0.01 | ||||
| MBP | 18.1 (10.7, 25.9) | < 0.01 | 7.64 (1.20, 14.5) | 0.02 | 10.3 (3.76, 17.2) | < 0.01 | 8.41 (0.33, 17.1) | 0.04 |
| MiBP | 20.5 (12.9, 28.7) | < 0.01 | 8.11 (2.01, 14.6) | < 0.01 | 7.11 (0.37, 14.3) | 0.04 | 14.6 (7.54, 22.1) | < 0.01 |
| MEP | −3.56 (−9.84, 3.16) | 0.29 | ||||||
| MCPP | 6.48 (0.17, 13.2) | 0.04 | ||||||
Models adjusted for urinary specific gravity, gestational age at sample collection, maternal age, Race/Ethnicity, education level, pre-pregnancy body mass index, and smoking during pregnancy. Models include controls only. Blank cells indicate that the exposure was not selected by adaptive elastic net for inclusion in the model. Abbreviations: DCP, dichlorophenols; BP3, benzophenone-3; PB, paraben; BPA, bisphenol-A; ΣDEHP, summed di-2-ethylhexyl phthalate metabolites; MBzP, mono-benzyl phthalate; MBP, mono-n-butyl phthalate; MiBP, mono-isobutyl phthalate; MEP, mono-ethyl phthalate; MCPP, mono-3-carboxypropyl phthalate; 8-OHdG, 8-hydroxydeoxyguanosine.