Table 2.
Patient characteristics
| Watering eyes (n=6) | No watering eyes (n=5) | p | ||||
|---|---|---|---|---|---|---|
| Median | (Range) | Median | (Range) | |||
| Age (year) | 70 | (44–80) | 63 | (43–67) | 0.297a | |
| Sex (male/female) | 6 | (3/3) | 5 | (3/2) | 1.000b | |
| Height (cm) | 156.15 | (147.0–178.0) | 156.2 | (154.3–164.0) | 0.535a | |
| Body weight (kg) | 46.75 | (40.0–58.8) | 47.6 | (31.2–78.4) | 0.548a | |
| Body surface area (m2) | 1.372 | (1.29–1.69) | 1.404 | (1.16–1.79) | 0.548a | |
| Serum creatinine (mg/dL) | 0.61 | (0.43–0.98) | 0.6 | (0.47–0.8) | 0.575a | |
| Initial dose (mg) | 100 | (80–120) | 100 | (80–120) | 0.535a | |
| Total dose (mg) | 13,440 | (4,880–19,790) | 13,440 | (5,820–22,360) | 0.548a | |
| Relative dose intensity (%) | 85.13 | (49.11–99.41) | 79.95 | (54.34–95.14) | 0.522a | |
| Treatment period (course) | 6.5 | (2–8) | 8 | (2–8) | 0.382a | |
| Treatment period (days) | 319 | (84–350) | 350 | (91–371) | 0.601a | |
Relative dose intensity = actual dose (mg) / standard dose (mg)
a Mann-Whitney U-test, b Fisher exact probability