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. 2019 Sep 5;10:4006. doi: 10.1038/s41467-019-11999-9

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — SD sequences in 720 genomes of 24 groups of prokaryotes. a Fractions of overlapping gene pairs that contain a SD motif upstream of the downstream gene, in the 3′-region of the upstream gene. Mean values and standard deviations are shown. b Fractions of leading genes that are preceded by a SD motif. Mean values and standard deviations are shown. c The quotient of the values shown in a and b, which represents the relative importance of the SD motif at downstream genes of overlapping gene pairs versus leading genes