Table 2.
Case | Organoid ID | Sex | Age | Lung cancer type | Differentiation | Subtype | Thawing test |
---|---|---|---|---|---|---|---|
1 | LCO-5 | F | 61 | Adenocarcinoma | Moderate | Papillary | nd |
2 | LCO-13 | M | 75 | Squamous cell carcinoma | Moderate | o | |
3 | LCO-15 | F | 75 | Adenocarcinoma | Moderate | Papillary | o |
4 | LCO-21 | F | 74 | Small cell carcinoma | o | ||
5 | LCO-22 | F | 55 | Adenocarcinoma | Poor | Micropapillary | x |
6 | LCO-28 | M | 78 | Squamous cell carcinoma | Moderate | o | |
7 | LCO-29 | M | 57 | Large cell neuroendocrine carcinoma | o | ||
8 | LCO-30 | M | 66 | Squamous cell carcinoma | Moderate | x | |
9 | LCO-34 | F | 64 | Adenocarcinoma | Moderate | Acinar | nd |
10 | LCO-36 | M | 68 | Adenocarcinoma | Well | Lepidic | nd |
11 | LCO-38 | M | 74 | Adenosquamous carcinoma | nd | ||
12 | LCO-42 | M | 82 | Squamous cell carcinoma | Moderate | o | |
13 | LCO-43 | M | 71 | Adenocarcinoma | Poor | Solid | o |
14 | LCO-49 | M | 75 | Adenocarcinoma | Poor | Solid | o |
15 | LCO-50 | M | 62 | Squamous cell carcinoma | Moderate | o | |
16 | LCO-51 | M | 60 | Adenocarcinoma | Poor | Micropapillary | o |
17 | LCO-52 | M | 72 | Squamous cell carcinoma | Moderate | o | |
18 | LCO-55 | M | 70 | Adenocarcinoma | Poor | Solid | o |
19 | LCO-56 | M | 69 | Adenocarcinoma | Well | Mucinous | x |
20 | LCO-58 | M | 63 | Adenocarcinoma | Poor | Solid | o |
21 | LCO-59 | M | 72 | Adenocarcinoma | Poor | Solid | nd |
22 | LCO-60 | M | 57 | Adenocarcinoma | Poor | Acinar | nd |
23 | LCO-61 | M | 66 | Adenocarcinoma | Well | Mucinous | x |
24 | LCO-62 | M | 63 | Adenocarcinoma | Moderate | Papillary | o |
25 | LCO-63 | M | 66 | Adenocarcinoma | Poor | Solid | nd |
26 | LCO-64 | F | 60 | Adenocarcinoma | Moderate | Acinar | nd |
27 | LCO-65 | M | 72 | Adenocarcinoma | Moderate | Acinar | nd |
28 | LCO-66 | M | 49 | Adenocarcinoma | Moderate | Acinar | nd |
29 | LCO-67 | F | 59 | Adenocarcinoma | Moderate | Enteric | nd |
30 | LCO-68 | M | 72 | Squamous cell carcinoma | Moderate | nd | |
31 | LCO-69 | F | 64 | Adenocarcinoma | Well | Lepidic | nd |
32 | LCO-70 | M | 64 | Adenocarcinoma | Poor | Sarcomatoid** | o |
33 | LCO-71 | M | 54 | Adenocarcinoma | Poor | Acinar | x |
34 | LCO-72 | M | 47 | Squamous cell carcinoma | Moderate | nd | |
35 | LCO-73 | F | 70 | Adenocarcinoma | Moderate | Acinar | nd |
36 | LCO-74 | M | 75 | Squamous cell carcinoma | Moderate | o | |
37 | LCO-75 | M | 69 | Small cell carcinoma | o | ||
38 | LCO-76 | M | 61 | Adenocarcinoma | Moderate | Papillary | nd |
39 | LCO-77 | M | 67 | Adenocarcinoma | Moderate | Papillary | nd |
40 | LCO-78 | M | 67 | Adenocarcinoma | Poor | Solid | nd |
41 | LCO-79 | F | 62 | Adenocarcinoma | Moderate | Mucinous | x |
42 | LCO-80 | M | 82 | Squamous cell carcinoma | Moderate | o | |
43 | LCO-81 | M | 64 | Adenocarcinoma | Poor | Solid | x |
44 | LCO-82 | M | 60 | Squamous cell carcinoma | Moderate | nd | |
45 | LCO-83 | M | 65 | Squamous cell carcinoma | Moderate | nd | |
46 | LCO-84 | M | 63 | Small cell carcinoma | o | ||
47 | LCO-85 | F | 64 | Adenocarcinoma | Moderate | Acinar | x |
48 | LCO-86 | M | 77 | Adenosquamous carcinoma | o | ||
49 | LCO-87 | M | 63 | Adenocarcinoma | Moderate | Papillary | o |
50 | LCO-88 | M | 76 | Large cell neuroendocrine carcinoma | x | ||
51 | NBO-89 | M | 50 | Normal bronchus | o | ||
52 | NBO-90 | F | 77 | Normal bronchus | o | ||
53 | LCO-91 | M | 65 | Small cell carcinoma | o | ||
54 | NBO-92 | F | 63 | Normal bronchus | nd | ||
55 | NBO-93 | M | 54 | Normal bronchus | nd | ||
56 | NBO-94 | M | 70 | Normal bronchus | nd | ||
57 | LCO-95 | M | 57 | Squamous cell carcinoma | Moderate | x | |
58 | LCO-96 | F | 71 | Adenocarcinoma | Moderate | Metastatic* | o |
59 | LCO-97 | M | 64 | Adenocarcinoma | Moderate | Papillary | x |
60 | LCO-98 | M | 75 | Squamous cell carcinoma | Moderate | x | |
61 | LCO-99 | M | 59 | Adenocarcinoma | Poor | Solid | o |
62 | LCO-100 | M | 58 | Adenocarcinoma | Moderate | Acinar | x |
63 | LCO-101 | F | 45 | Adenocarcinoma | Moderate | Acinar | nd |
64 | LCO-102 | M | 70 | Adenocarcinoma | Moderate | Acinar | nd |
65 | LCO-103 | M | 76 | Adenocarcinoma | Moderate | Acinar | nd |
66 | LCO-104 | M | 62 | Adenocarcinoma | Poor | Sarcomatoid** | x |
67 | LCO-105 | F | 68 | Adenocarcinoma | Moderate | Papillary | nd |
68 | LCO-106 | M | 67 | Adenocarcinoma | Moderate | Mucinous | o |
69 | LCO-107 | F | 62 | Adenosquamous carcinoma | x | ||
70 | LCO-108 | M | 63 | Adenocarcinoma | Moderate | Acinar | nd |
71 | LCO-109 | F | 52 | Squamous cell carcinoma | Moderate | o | |
72 | LCO-110 | M | 52 | Adenocarcinoma | Moderate | Metastatic* | o |
73 | LCO-111 | M | 70 | Large cell neuroendocrine carcinoma | o | ||
74 | LCO-112 | M | 60 | Adenocarcinoma | Moderate | Metastatic* | o |
75 | LCO-113 | M | 62 | Adenocarcinoma | Moderate | Mucinous | o |
76 | LCO-114 | M | 64 | Small cell carcinoma | o | ||
77 | LCO-115 | M | 77 | Adenocarcinoma | Moderate | Acinar | x |
78 | LCO-116 | M | 80 | Squamous cell carcinoma | Moderate | o | |
79 | LCO-117 | M | 63 | Adenocarcinoma | Moderate | Metastatic* | o |
80 | LCO-118 | M | 57 | Adenocarcinoma | Moderate | Papillary | x |
81 | LCO-119 | M | 63 | Adenocarcinoma | Moderate | Acinar | o |
82 | LCO-120 | M | 59 | Adenocarcinoma | Moderate | Metastatic* | o |
83 | LCO-121 | M | 71 | Adenocarcinoma | Moderate | Papillary | o |
84 | LCO-122 | M | 81 | Adenocarcinoma | Moderate | Metastatic* | o |
85 | LCO-123 | M | 42 | Adenocarcinoma | Moderate | Metastatic** | nd |
LCO lung cancer organoid, NBO normal bronchial organoid, nd not done, O pass, X fail, Metastatic* metastatic colonic adenocarcinoma, Metastatic** metastatic lung adenocarcinoma, biopsy, Sarcomatoid** adenocarcinoma with sarcomatoid feature