Table 1.
Baseline Demographic and Laboratory Profile of Post-Kasai Portoenterostomy Patients.
| Parameters | Operated at our centre (n = 42) | Operated at other centres (n = 37) | P value |
|---|---|---|---|
| Age at presentation (days) | 83.2 ± 29.6 | 75.2 ± 27.4 | 0.195 |
| Age at KPE (days) | 89.9 ± 30 | 89.8 ± 30 | 0.958 |
| Gender, male/female | 27/15 | 23/14 | |
| Total bilirubin (mg/dl) | 11.4 ± 3.7 | 9.6 ± 3 | 0.04 |
| Aspartate aminotransferase (IU/ml) | 322.8 ± 209.9 | 306.9 ± 355.6 | 0.862 |
| Alanine aminotransferase (IU/ml) | 223.7 ± 184.8 | 217.4 ± 164.4 | 0.949 |
| Alkaline phosphatase (IU/ml) | 588.7 ± 268.4 | 839.9 ± 509.7 | 0.029 |
| Gamma-glutamyl transferase (IU/ml) | 599.3 ± 507.2 | 663.8 ± 517 | 0.480 |
| Serum albumin (G/dl) | 3.4 ± 0.4 | 3.3 ± 0.5 | 0.204 |
| Transient elastography (kPa) | 23.6 ± 19.5 | NA | |
| Imaging findings n (%) | |||
| Nonvisualization of CBD | 42 (100) | ||
| Nonvisualization of GB | 30 (71.4) | ||
| Pseudo gall bladder | 12 (28.6) | ||
| Triangular cord sign | 8 (19) | NA | |
| Splenic malformation | 3 (7.1) | ||
| Cholangitis after KPE | 26 (61.9) | 30 (81.1) | 0.083 |
| Use of steroids after KPE | 18 (42.9) | 8 (21.6) | 0.06 |
| Decrease in bilirubin to < 2 mg/dl within 6 months of KPE | 16 (38.1) | 13 (35.1) | 0.819 |
CBD, common bile duct; GB, gall bladder; ILBS, Institute of Liver and Biliary Sciences; kPa, kilo-Pascals; KPE, Kasai portoenterostomy.