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. 2019 Aug 29;5(8):e02370. doi: 10.1016/j.heliyon.2019.e02370

Fig. 3.

Fig. 3

Assessment of RB51-specific IgG titers in serum from VPEAR and RB51 vaccinated animals following initial vaccination and RB51 boost. Time course of RB51-specific total IgG in the serum of naïve (white bars), VPEAR- (black bars) and RB51-vaccinated (gray bars) animals at different time points following (A) initial vaccination and (B) RB51 boost. (C) Assessment of RB51-specific IgG isotypes, IgG1 and IgG2 in serum at 8 weeks post-initial vaccination and 8 weeks post-RB51 boost. (D) Assessment of RB51-specific IgG avidity at 8 weeks post-initial vaccination and 8 weeks post-RB51 boost Lower-case letters denote statistical significance between treatment groups at each individual timepoint, (*) denotes statistical significance as indicated by a p value ≤0.05.