Table 2.
Retinal layer thickness at baseline.
| All eyes N = 1570 |
MSON before
BL N = 451 |
No MSON before
BL N = 1119 |
HCs N = 184 |
p valuea MSON vs HC |
p valuea No MSON vs HCs |
p valuea No MSON vs MSON |
|
|---|---|---|---|---|---|---|---|
| INL (mm3) | 0.98 (0.08) | 0.99 (0.08) | 0.97 (0.08) | 0.96 (0.09) | .001 | .066 | .001 |
| GCIPL (mm3) | 1.79 (0.26) | 1.62 (0.25) | 1.86 (0.23) | 1.97 (0.19) | <.001 | <.001 | <.001 |
| pRNFL (µm) | 91.4 (15.8) | 81.4 (17.5) | 95.2 (13.2) | 95.8 (9.1) | <.001 | .106 | <.001 |
BL: baseline visit; HC: healthy controls; GCIPL: ganglion cell-inner plexiform layer; INL: inner nuclear layer; MSON: multiple sclerosis–related optic neuritis; pRNFL: peripapillary retinal nerve fibre layer.
aGeneralised estimation equation analyses, unadjusted.