Table 3.

Prostate cancer.

Molecular Feature	Target of Therapies	Drug(s)
Androgen pathways	LHRH ligands	Goserelin, Leuproline, Triptorelin, Abarelix, Aegarelix;
Androgen pathways	Enzyme CYP17	Abiraterone, Ketoconazole;
Androgen pathways	Androgen receptor (AR)	cyproterone acetate, bicalutamide, flutamide, nilutamide, enzalutamide.
Osteoclast proliferation	Receptor activator of nuclear factor kappa-B ligand (RANKL)	Denosumab
Checkpoint inhibitors	CTLA-4, PD1, PD1 ligands PD-L1/PD-L2	Ipilimumab, nivolumab, pembrolizumab, atezolizumab

Abbreviations: CTLA, a cytotoxic T-lymphocyte associated protein 4; LHRH, luteinizing hormone–releasing hormone; PD1, programmed death 1 receptor.