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. 2019 Sep 4;17(3):1559325819872583. doi: 10.1177/1559325819872583

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© The Author(s) 2019

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 8. — CLSM images of BT474 and MCF7 cells. BT474 and MCF7 cells were incubated with fluorescence-labeled PPLNs, eTmab-PPLNs, or Tmab + eTmab-PPLNs. Among them, Tmab + eTmab-PPLNs were represented free nonfluorescent labeled Tmab was added prior to the addition of double fluorescence labeled eTmab-PPLNs. CLSM indicates confocal laser scanning microscopy; eTmab-PPLNs, electrostatically conjugated trastuzumab-bearing poly (d, l-lactide-co-glycolide)/polyethylenimine/lipid nanoparticles; PPLNs, poly (d, l-lactide-co-glycolide)/polyethylenimine/lipid nanoparticles; Tmab, trastuzumab.