Table 1.

Effect of PLGA-to-egg PC Ratio on Characteristics of PPLNs.^a

PLGA:Egg PC (wt/wt)	Size, nm	PDI	ζ potential, mV	EE, %
8:0	191.0 ± 1.901	0.103 ± 0.039	−5.14 ± 0.310	34.02 ± 0.955
7:1	181.7 ± 3.554	0.147 ± 0.041	−6.09 ± 0.906	39.88 ± 6.756
6:2	171.7 ± 1.007	0.114 ± 0.041	−6.55 ± 0.688	17.23 ± 0.110
5:3	157.3 ± 1.150	0.081 ± 0.056	−9.89 ± 1.22	10.65 ± 0.630
4:4	152.4 ± 4.678	0.156 ± 0.046	−10.2 ± 0.273	13.85 ± 0.296

Abbreviations: EE, encapsulation efficiency; egg PC, egg phosphatidylcholine; PDI, polydispersity index; PLGA, poly (d, l-lactide-co-glycolide); PPLNs, PLGA/polyethylenimine /lipid nanoparticles; SD, standard deviation.

^a Data are expressed as mean ± SD (n = 3).