Table 4.
Formulation | Size, nm | PDI | ζ Potential, mV | EE, % |
---|---|---|---|---|
PPLNs | 193.4 ± 4.204 | 0.087 ± 0.017 | 23.6 ± 1.77 | 35.06 ± 5.703 |
eTmab-PPLNs | 217.4 ± 13.36 | 0.116 ± 0.057 | 0.056 ± 0.115 | 31.27 ± 3.215 |
Abbreviations: EE, encapsulation efficiency; eTmab-PPLNs, electrostatically conjugated trastuzumab-bearing PPLNs; PDI, polydispersity index; PPLNs, poly (d, l-lactide-co-glycolide)/polyethylenimine/lipid nanoparticles; SD, standard deviation.
a Data are represented as mean ± SD (n = 3).