Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jun 17;28(8):1076–1084. doi: 10.1177/0963689719857085

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

PMC Copyright notice

Fig. 4. — The formation of autophagy bubbles revealed by transmission electron microscopy. A1–D1 ×10,000; A2–D2 ×30,000. A1 and A2 are SH-SY5Y cells. They showed abundant and normal morphology of cytoplasm, cell organelles and nuclei. B1 and B2 were from the AD model cells. There were abundant autophagic vacuoles and lysosomes. C1 and C2 were from the negative control group; the autophagic vacuoles are similar to the AD cell model. After transfection with miRNA-101a, the autophagic vacuoles and lysosomes numbered fewer than the AD model cells, D1 and D2.

AD: Alzheimer’s disease.