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. 2019 Mar 6;28(8):985–1001. doi: 10.1177/0963689719834873

Fig. 7.

Fig. 7.

Inhibiting NHE1 by chemical inhibitor and genetic-knockdown alleviates blood-brain barrier (BBB) injury, brain edema and neurological impairment in rats following SAH. (A) Western blot analysis measures the protein levels of albumin in brain tissues of rats in various groups. (B) Quantification of relative protein levels of albumin in various groups; mean values of Sham group are normalized to 1.0. (C) Bar graphs showed the effects of NHE1 on brain water content of rats in various groups. (D) The neurological scores in various groups are shown; data are shown as individual data. In (B), (C) and (D), all data are presented as mean ± SEM; *p < 0.05 vs. Sham group; ns, no significant difference vs. SAH group; # p < 0.05 vs. SAH + Vehicle group; & p < 0.05 vs. SAH + Si-NC group; @ p < 0.05 vs. SAH + Vector group; n = 6.