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. 2019 Aug 30;10:2073. doi: 10.3389/fimmu.2019.02073

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Copyright © 2019 Sanz-Ortega, Rojas, Portilla, Pérez-Yagüe and Barber.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Phenotypic and functional analysis of NK-92MI cells after their association with MNPs. (A) Quantification (MFI, mean fluorescence intensity) of the expression of relevant cell-surface markers in NK-92MI cells, after incubation with MNPs and representative histograms. (B) Degranulation capacity of NK-92MI cells, after being treated with different concentrations of MNPs and after exposure to a range of stimuli. (C) Quantification of the percentage of IFN-γ⁺ NK-92MI cells after MNP treatment and exposure to a number of stimuli. The data (mean ± SD) are representative of three independent experiments, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.