Table 1.
General characteristics of CHC patients and control group
| Parameter | CHC patients n = 63 | Men n = 29 (46%) | Women n = 34 (54%) | p* | Control group n = 30 | p** |
|---|---|---|---|---|---|---|
| Age (years) | 46.6 ±14.6 | 48.2 ±16.6 | 45.3 ±12.8 | NS | 47.9 ±14.8 | NS |
| Body mass index (kg/m2) | 24.8 ±3.0 | 25.7 ±2.6 | 24.0 ±3.1 | 0.02 | 23.9 ±3.3 | NS |
| Waist circumference (cm) | 87.8 ±11.2 | 87.8 ±11.2 | 79.4 ±12.5 | 0.03 | 85.5 ±8.7 | NS |
| SBP (mmHg) | 135.0 ±18.8 | 135.0 ±18.8 | 125.0 ±12.5 | 0.02 | 115.0 ±10.5 | NS |
| DBP (mmHg) | 79.1 ±8.9 | 79.1 ±8.9 | 80.0 ±9.5 | NS | 77.1 ±6.6 | NS |
| Fasting insulin (μU/l) | 11.6 ±9.6 | 10.6 ±6.3 | 12.4 ±11.8 | NS | 10.0 ±4.5 | NS |
| Fasting glucose (mg/dl) | 93.7 ±16.0 | 95.1 ±16.4 | 92.6 ±15.8 | NS | 80.8 ±9.0 | NS |
| HOMA-IR | 2.9 ±2.7 | 2.5 ±1.3 | 3.4 ±3.5 | NS | 2.0 ±0.5 | 0.03 |
| Total bilirubin (μmol/l) | 14.3 ±8.7 | 15.1 ±4.1 | 13.6 ±11.2 | NS | 9.7 ±3.5 | 0.02 |
| GGT (U/l) | 80.7 ±86.9 | 104.8 ±119.2 | 60.2 ±34.5 | 0.04 | 26.0 ±5.5 | 0.04 |
| ALT (U/l) | 75.4 ±44.5 | 83.2 ±50.8 | 98.8 ±37.7 | NS | 25.6 ±4.3 | 0.001 |
| AST (U/l) | 51.7 ±25.3 | 54.2 ±28.5 | 59.5 ±22.5 | NS | 24.1 ±3.8 | 0.004 |
| Total cholesterol (mg/dl) | 187.8 ±117.1 | 199.5 ±170.6 | 179.4 ±53.8 | NS | 174.6 ±33.2 | NS |
| LDL cholesterol (mg/dl) | 97.6 ±45.6 | 85.0 ±38.3 | 107.6 ±49.0 | NS | 94.5 ±20.2 | NS |
| HDL cholesterol (mg/dl) | 53.7 ±24.6 | 50.3 ±27.8 | 56.0 ±22.3 | NS | 44.0 ±12.8 | NS |
| Triglycerides (mg/dl) | 131.9 ±57.8 | 136.2 ±56.3 | 129.0 ±59.6 | NS | 139.0 ±45.0 | NS |
| CRP (mg/dl) | 1.7 ±1.2 | 1.6 ±1.1 | 1.8 ±1.4 | NS | 1.5 ±1.4 | NS |
| HCV viral load (IU/l) | 2053301 ±364614 | 2781433 ±487426 | 1432246 ±1976597 | NS |
SBP – systolic blood pressure, DBP – diastolic blood pressure
*
p – men vs. women
**
p – CHC patients vs. controls