Table 1.
Relative hierarchy | Mother cluster size (cluster annotation) | No. of Mother Clusters (cluster annotation) | No. of main clusters | No. of tiny clusters | Tiny clusters – Average size | Tiny clusters – Cumulative size | Orphan voxelsa | Reachability threshold |
---|---|---|---|---|---|---|---|---|
0 | 4 (#1, #6, #80, #71) | 16 | 123 | 8.59 | 1056 | 0 | 1.25 × e−3 | |
1 | 25961 (#1) | 2 (#1.1, #1.5) | 18 | 62 | 10.6 | 656 | 547 | 9.47 × e−4 |
2 | 14,183 (#1.1) | 1 (#1.1.1) | 18 | 35 | 13.2 | 463 | 134 | 8.05 × e−4 |
2 | 4121 (#1.5) | 0 | 20 | 62 | 13.4 | 834 | 255 | 3.41 × e−4 |
3 | 8818 (#1.1.1) | 1 (#1.1.1.1) | 20 | 26 | 11.0 | 287 | 103 | 6.20 × e−4 |
4 | 2703 (#1.1.1.1) | 0 | 13 | 83 | 12.5 | 1040 | 508 | 0 |
1 | 17,529 (#6) | 2 (#6.61, #6.84) | 21 | 52 | 9.65 | 502 | 622 | 1.06 × e−3 |
2 | 4829 (#6.61) | 0 | 12 | 106 | 11.5 | 1215 | 1185 | 0 |
2 | 2766 (#6.84) | 0 | 8 | 81 | 9.6 | 776 | 1562 | 0 |
1 | 4442 (#71) | 0 | 7 | 121 | 9.82 | 1188 | 1542 | 0 |
1 | 9130 (#80) | 1 (#80.588) | 18 | 108 | 11.0 | 1186 | 1879 | 8.72 × e−4 |
2 | 4520 (#80.588) | 1 (#80.588.1545) | 10 | 58 | 10.4 | 606 | 722 | 1.08 × e−19 |
3 | 2319 (#80.588.1545) | 1 (#80.588.1545)b | 0 | 0 | 0 | 0 |
An iterative scheme was applied for hierarchical clustering: the reachability threshold was initially set to form 20 mother/main clusters along with any number of tiny clusters. The same scheme was repeated for any mother cluster formed among subdivisions. Eventually, the brain was parcellated into 1 mother, 181 main, and 917 tiny clusters.
Mother clusters referred to those >1850 voxels (~50 cm3); main clusters were > 37 voxels (~1 cm3); and tiny clusters were ≤ 37 voxels.
Cluster size are presented in voxel, where each voxel is 0.027 cm3.
During subdivision clustering process, some voxels could not be assigned to any of sub-clusters generated at corresponding hierarchical level, and are referred to as “orphan” voxels. The column depicts the total number of orphan voxels generated at corresponding sub-clustering level.
One of the mother clusters at the 3rd hierarchical level (#80.588.1545) could not be resolved to smaller main or tiny clusters.