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. 2019 Aug 30;9:825. doi: 10.3389/fonc.2019.00825

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Copyright © 2019 Lindell Jonsson, Erngren, Engskog, Haglöf, Arvidsson, Hedeland, Petterson, Laurell and Nestor.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PCA score plot from the metabolic profiling in negative ionization mode, the two SCC cell lines are separated along the second principal component (PC2). Along the first component (PC1) there is some separation between the controls and irradiated cells, however, no clear clustering. UM-SCC-74A Control (■), UM-SCC-74A Rapid response (4 h after 2 Gy irradiation) (▴), UM-SCC-74A Intermediate response (24 h after 2 Gy irradiation) (∙), UM-SCC-74B Control (□), UM-SCC-74B Rapid response (▵), and UM-SCC-74B Intermediate response (°).