Table 1.
Significantly different metabolites (p < 0.05) between non-irradiated cell lines UM-SCC-74A and UM-SCC-74B are presented as fold changes (95% confidence).
| POSITIVE IONIZATION | |
| Metabolite ID | A control vs. B control |
| 5-phosphoribosylamine | −2.10 ± 0.66 |
| DMAPP | 2.39 ± 1.20 |
| NEGATIVE IONIZATION | |
| Metabolite | A control vs. B control |
| Tyrosine | −2.01 ± 0.74 |
| Valine | −3.35 ± 1.72 |
| Alanine, sarcosine, beta-alanine | −3.39 ± 1.95 |
| Homoserine, threonine | −6.80 ± 5.20 |
| Hydantoin-5-propionic acid | −2.14 ± 0.72 |
| Diphosphoinositol pentakisphosphate | −2.35 ± 1.02 |
| Myo-inositol hexakisphosphate | −2.54 ± 1.21 |
| Leukotriene D4 | 14.54 ± 5.01 |
| Leukotriene E4 | −4.21 ± 1.67 |
| Xanthine | 39.62 ± 14.12 |
| Guanosine | 12.71 ± 9.35 |
| Inosine | 3.83 ± 2.20 |
| Cytidine | 2.67 ± 1.22 |
| Nicotinic acid mononucleotide | −5.93 ± 2.50 |
| Nicotinic acid | 2.30 ± 0.93 |
| Niacinamide | −2.13 ± 0.62 |
| Pantothenic acid | −3.17 ± 1.59 |
| 2-Aminomuconic acid semialdehyde | 1.96 ± 0.68 |
The p-values were calculated using ANOVA followed by a Tukey test and the fold changes were calculated using Fieller's theorem for a 95% confidence interval. A positive fold change indicates a higher level in 74A UM-SCC-74A as compared to 74B UM-SCC-74B