Table 2.
Day | Placeboc | Sarolaner | % efficacy | ||
---|---|---|---|---|---|
Meand | Range | Mean | Range | ||
2 | 26.8 (27.9) | 18–49 | 0 | 0–0 | 100 |
7 | 31.9 (32.5) | 22–40 | 0 | 0–0 | 100 |
14 | 36.8 (37.4) | 30–48 | 0 | 0–0 | 100 |
21 | 26.2 (27.3) | 14–35 | 0 | 0–0 | 100 |
28 | 30.6 (31.4) | 19–41 | 0 | 0–0 | 100 |
35 | 39.2 (39.9) | 26–49 | 0 | 0–0 | 100 |
aLaboratory tick strain used was obtained from Clinvet, Bloemfontein, Free State, South Africa
bCommercial chewable tablet formulation (Simparica™) containing sarolaner as active ingredient
cChewable tablet with vehicle compounds only
dMean values indicated as: geometric (arithmetic)
Note: Difference in mean tick count was significant (ANOVA, F(1, 15) = 69.41, P < 0.0001) in all instances) for all assessment days